Showing posts with label WHO. Show all posts
Showing posts with label WHO. Show all posts

Saturday, 16 August 2014

WOLRD MOVES TO CUT OFF WEST AFRICA AS EBOLA PANIC INCREASES




Millions of ordinary Africans, facing panicky quarantine orders and cancelled flights, are beginning to pay a heavy price for the world’s alarmist myths about the Ebola crisis.

Far from the centre of the Ebola outbreak, airlines and governments are imposing restrictions on African travellers, ignoring the advice of medical experts. Korean Air Lines became the latest example on Thursday, suspending all of its flights to Kenya, a country that doesn’t have a single Ebola case and is located 5,000 kilometres from the danger zone.

Other fear-based reactions are multiplying. Nigerian athletes were placed into quarantine at the Summer Youth Olympic Games in China, prompting them to quit in protest. Ghana is proposing a ban on all “public gatherings.” Zambia is banning entry to anyone from Liberia, Sierra Leone, Guinea and Nigeria, the four West African nations where Ebola is present. British Airways and Emirates have suspended flights to some West African cities, and Ivory Coast is blocking ship cargo to the three hardest-hit countries, raising fears of food and fuel shortages.

The heavy-handed travel bans are provoking sharp criticism from experts at the World Health Organization and Médecins sans frontières (Doctors Without Borders). The flight cancellations are an overreaction that could make the situation worse, hindering the efforts to help Ebola-affected regions, the WHO says.

“WHO disappointed when airlines stop flying to West Africa,” the organization said in a tweet on Thursday. “Hard to save lives if we & other health workers cannot get in.”

Stephen Cornish, executive director of MSF Canada, said the suspension of African flights will heighten the risks of Ebola spreading to other countries, since it will become more difficult to send medical and epidemiological specialists to the Ebola zone.

“We should not be cutting off the affected countries’ lifelines in a misguided effort at home society protection,” he said in an e-mail. “The oversensationalism and hype around Ebola has not helped the public’s understanding of how the disease is spread.”

Some of the panic is due to fears that Ebola could spread by air travel, as it did in one case already, when a Liberian with the Ebola virus flew to Lagos and died there, infecting several other people. But the risk of Ebola transmission during air travel “remains low,” the WHO said in a statement on Thursday.

Unlike influenza or tuberculosis, Ebola is not airborne and can only be transmitted by direct contact with the body fluids of someone who is sick with the disease. “On the small chance that someone on the plane is sick with Ebola, the likelihood of other passengers and crew having contact with their body fluids is even smaller,” the WHO said.

“Usually when someone is sick with Ebola, they are so unwell that they cannot travel. WHO is therefore advising against travel bans to and from affected countries.”

The global health organization is bracing for more panic and fear. “In the coming days there will be rumours all over the world,” WHO senior official Isabelle Nuttall told a briefing in Geneva on Thursday.

The travel restrictions aren’t just hampering the medical response to Ebola. They could also damage the economies of many African nations, scaring away investors and damaging trade.

Economic analysts are already warning that the Ebola crisis could slow the growth rates in the three worst-affected countries by up to 2 percentage points. Some farmers have abandoned their fields, cross-border markets have been shut down and several major mining companies have scaled back their operations or postponed expansion plans.

The Ebola crisis could also create shortages of food, fuel and other supplies because the nearest big port, Abidjan in Ivory Coast, has announced a ban on all ships from the Ebola-affected countries. Some media in Liberia are calling it an “economic blockade.” The country’s authorities have said they are worried that rice importers could be heavily affected by the ban, a Liberian newspaper reported on Thursday.

Liberia and Sierra Leone are especially vulnerable to the economic impact of the Ebola crisis, including the damage to trade and air travel, because they are still recovering from devastating civil wars that ended barely a decade ago.

Wednesday, 13 August 2014

UNTESTED DRUGS CAN BE USED TO TREAT EBOLA VIRUS, SAYS THE WHO


Ethical to use untested Ebola drugs, says WHO

The outbreak has killed over 1,000 people
Untested drugs can be used to treat patients infected with the Ebola virus, the World Health Organization says.

The WHO said it was ethical in light of the scale of the outbreak and high number of deaths - more than 1,000 people have died in West Africa.

The statement was made after its medical experts met in Switzerland on Monday to discuss the issue.

But officials have warned that there were very limited supplies of potential treatments.

Dr Marie-Paule Kieny from the WHO said that there has been "unanimous agreement" among experts

The WHO said that where experimental treatments are used there must be informed consent and the results of the treatment collected and shared.

In a statement, it said: "In the particular circumstances of this outbreak, and provided certain conditions are met, the panel reached consensus that it is ethical to offer unproven interventions with as yet unknown efficacy and adverse effects, as potential treatment or prevention."

But the organisation conceded that there were still a lot of questions to be answered including how data could be gathered effectively while the focus remained on providing good medical care.

It was also unclear where the funding for the treatment would come from.

Last week the WHO declared the Ebola outbreak was a global health emergency.


The move came as Liberia said it was getting an experimental drug, Zmapp, after requests to the US government.

But the WHO said there were only 12 doses.

Zmapp has been used on two US aid workers who have shown signs of improvement, although it is not certain what role the medication played in this.

A Roman Catholic priest, infected with Ebola in Liberia, who died after returning home to Spain is also thought to have been given the drug.

However, the drug has only been tested on monkeys and has not yet been evaluated for safety in humans.

What drugs exist currently ?
There a handful of drugs that have been shown to work well in animals.

One is Zmapp - the drug requested by the Liberian government. This contains a cocktail of antibodies that attack proteins on the surface of the virus.

Only one drug has moved onto early safety testing in humans. Known as TKM-Ebola this interrupts the genetic code of the virus and prevents it from making disease causing proteins.

The drug was trialled in healthy volunteers at the beginning of 2014 but the American medicines regulator asked for further safety information. The manufacturer says human studies may soon resume.

Another option would be to use serum from individuals who have survived the virus - this is a part of the blood that may contain particles able to neutralise the virus.

Vaccines to protect against acquiring the disease have also been shown to work in primates. American authorities are considering fast-tracking their development and say they could be in use in 2016. Trials are likely to start soon according to the WHO.

But experts warn ultimately the only way to be sure a drug or vaccine is effective is to see if it works in countries affected by Ebola.

There is no cure for Ebola, which has infected at least 1,779 people since the outbreak was first reported in Guinea in February.

'Hard place'
The Liberian government said it was aware of the risks associated with Zmapp, but the alternative was to allow many more people to die.

"The alternative for not testing this is death, a certain death," Information Minister Lewis Brown told the BBC.

"This is not even the rock and the hard place for us.

"We think those who have been infected should be given the chance to have that tested on them if they give their consent to do so.

"We know there may be risks associated with it," the minister added, "but choosing a risk and choosing dying I am sure many would prefer to see that risk happen".

Ebola's initial flu-like symptoms can lead to external haemorrhaging from areas like eyes and gums, and internal bleeding which can lead to organ failure. Patients have a better chance of survival if they receive early treatment.

Ebola virus disease (EVD)
Symptoms include high fever, bleeding and central nervous system damage
Fatality rate can reach 90% - but the current outbreak is about 55%
Incubation period is two to 21 days
There is no vaccine or cure
Supportive care such as rehydrating patients who have diarrhoea and vomiting can help recovery
Fruit bats are considered to be virus' natural host

                                                                                                                          -Source: BBC News